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Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4

Background: Oral commensals contribute to microbe-host symbiosis in periodontal homeostasis, and Porphyromonas gingivalis (P. gingivalis) as the keystone pathogen critically accounts for the shift of symbiosis to dysbiosis and periodontal destruction. Nucleotide-binding oligomerization domain (NOD)-...

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Detalles Bibliográficos
Autores principales: Ding, Pei-Hui, Yang, Meng-Xin, Wang, Na-Na, Jin, Li-Jian, Dong, Yan, Cai, Xia, Chen, Li-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438778/
https://www.ncbi.nlm.nih.gov/pubmed/32903638
http://dx.doi.org/10.3389/fmicb.2020.01881