Rescue of a Vaccinia Virus Mutant Lacking IFN Resistance Genes K1L and C7L by the Parapoxvirus Orf Virus

Type 1 interferons induce the upregulation of hundreds of interferon-stimulated genes (ISGs) that combat viral replication. The parapoxvirus orf virus (ORFV) induces acute pustular skin lesions in sheep and goats and can reinfect its host, however, little is known of its ability to resist IFN. Vacci...

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Detalles Bibliográficos
Autores principales: Riad, Sherief, Xiang, Yan, AlDaif, Basheer, Mercer, Andrew A., Fleming, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438785/
https://www.ncbi.nlm.nih.gov/pubmed/32903701
http://dx.doi.org/10.3389/fmicb.2020.01797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438785/
https://www.ncbi.nlm.nih.gov/pubmed/32903701
http://dx.doi.org/10.3389/fmicb.2020.01797

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