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Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics
Genes for endoplasmic reticulum (ER)-shaping proteins are among the most commonly mutated in hereditary spastic paraplegia (HSP). Mutation of these genes in model organisms can lead to disruption of the ER network. To investigate how the physiological roles of the ER might be affected by such disrup...
Autores principales: | Oliva, Megan K., Pérez-Moreno, Juan José, O’Shaughnessy, Jillian, Wardill, Trevor J., O’Kane, Cahir J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438849/ https://www.ncbi.nlm.nih.gov/pubmed/32903680 http://dx.doi.org/10.3389/fnins.2020.00816 |
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