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CCR2 Inhibition Reduces Neurotoxic Microglia Activation Phenotype After Japanese Encephalitis Viral Infection

Controlling the proinflammatory response of microglia by targeting chemokines (C-C motif) receptor 2 (CCR2) could be an important therapeutic approach for Japanese encephalitis virus (JEV) infection. Here, through JEV infection to BV2 microglia and young BALB/c mice, we investigated that CCR2 is hig...

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Detalles Bibliográficos
Autores principales: Singh, Swati, Singh, Gajendra, Tiwari, Swasti, Kumar, Alok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439097/
https://www.ncbi.nlm.nih.gov/pubmed/32903799
http://dx.doi.org/10.3389/fncel.2020.00230