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Coronary endothelial dysfunction prevented by small-conductance calcium-activated potassium channel activator in mice and patients with diabetes

OBJECTIVE: To investigate coronary endothelial protection of a small-conductance calcium-activated potassium (SK) channel activator against a period of cardioplegic-hypoxia and reoxygenation (CP-H/R) injury in mice and patients with diabetes (DM) and those without diabetes (nondiabetic [ND]). METHOD...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiqi, Shi, Guangbin, Liu, Yuhong, Xing, Hang, Kabakov, Anatoli Y., Zhao, Amy S., Agbortoko, Vahid, Kim, Justin, Singh, Arun K., Koren, Gideon, Harrington, Elizabeth O., Sellke, Frank W., Feng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439127/
https://www.ncbi.nlm.nih.gov/pubmed/32199659
http://dx.doi.org/10.1016/j.jtcvs.2020.01.078