Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model

The gut-brain axis is bidirectional, and gut microbiota influence brain disorders including Alzheimer’s disease (AD). CCAAT/enhancer binding protein β/asparagine endopeptidase (C/EBPβ/AEP) signaling spatiotemporally mediates AD pathologies in the brain via cleaving both β-amyloid precursor protein a...

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Detalles Bibliográficos
Autores principales: Chen, Chun, Ahn, Eun Hee, Kang, Seong Su, Liu, Xia, Alam, Ashfaqul, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439296/
https://www.ncbi.nlm.nih.gov/pubmed/32832679
http://dx.doi.org/10.1126/sciadv.aba0466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439296/
https://www.ncbi.nlm.nih.gov/pubmed/32832679
http://dx.doi.org/10.1126/sciadv.aba0466

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