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Targeting brain metastases with ultrasmall theranostic nanoparticles, a first-in-human trial from an MRI perspective

The use of radiosensitizing nanoparticles with both imaging and therapeutic properties on the same nano-object is regarded as a major and promising approach to improve the effectiveness of radiotherapy. Here, we report the MRI findings of a phase 1 clinical trial with a single intravenous administra...

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Detalles Bibliográficos
Autores principales: Verry, Camille, Dufort, Sandrine, Lemasson, Benjamin, Grand, Sylvie, Pietras, Johan, Troprès, Irène, Crémillieux, Yannick, Lux, François, Mériaux, Sébastien, Larrat, Benoit, Balosso, Jacques, Le Duc, Géraldine, Barbier, Emmanuel L., Tillement, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439298/
https://www.ncbi.nlm.nih.gov/pubmed/32832613
http://dx.doi.org/10.1126/sciadv.aay5279