Cargando…

Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA

Human induced pluripotent stem cell (h-iPSC)–derived endothelial cells (h-iECs) have become a valuable tool in regenerative medicine. However, current differentiation protocols remain inefficient and lack reliability. Here, we describe a method for rapid, consistent, and highly efficient generation...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Kai, Lin, Ruei-Zeng, Hong, Xuechong, Ng, Alex H., Lee, Chin Nien, Neumeyer, Joseph, Wang, Gang, Wang, Xi, Ma, Minglin, Pu, William T., Church, George M., Melero-Martin, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439318/
https://www.ncbi.nlm.nih.gov/pubmed/32832668
http://dx.doi.org/10.1126/sciadv.aba7606