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Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA
Human induced pluripotent stem cell (h-iPSC)–derived endothelial cells (h-iECs) have become a valuable tool in regenerative medicine. However, current differentiation protocols remain inefficient and lack reliability. Here, we describe a method for rapid, consistent, and highly efficient generation...
Autores principales: | Wang, Kai, Lin, Ruei-Zeng, Hong, Xuechong, Ng, Alex H., Lee, Chin Nien, Neumeyer, Joseph, Wang, Gang, Wang, Xi, Ma, Minglin, Pu, William T., Church, George M., Melero-Martin, Juan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439318/ https://www.ncbi.nlm.nih.gov/pubmed/32832668 http://dx.doi.org/10.1126/sciadv.aba7606 |
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