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Improvement of digital PCR conditions for direct detection of KRAS mutations

BACKGROUND: In standard analytical conditions, an isolation step is essential for circulating tumor DNA (ctDNA) analysis. The necessity of this step becomes unclear with the development of highly sensitive detection methods. The aim of this study was to evaluate ctDNA mimetic nDNA detection as refer...

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Detalles Bibliográficos
Autores principales: Lee, Jina, Kim, Ji Hyun, Kang, Sun Hyung, Yoo, Hee Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439326/
https://www.ncbi.nlm.nih.gov/pubmed/32329932
http://dx.doi.org/10.1002/jcla.23344