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Significant association between DHFR promoter methylation and ischemic stroke in a Chinese hypertensive population

OBJECTIVE: DHFR encodes dihydrofolate reductase, a major enzyme in the metabolism of folate, and is a candidate gene for ischemic stroke (IS). Therefore, we aimed to investigate the association between DHFR promoter methylation and IS in a Chinese population with primary hypertension. METHODS: Quant...

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Detalles Bibliográficos
Autores principales: Hu, Jingcen, Zhu, Hong, Xu, Guodong, Chen, Zhu, Li, Lian, Wang, Shuyu, Deng, Hongxia, Bao, Xiaoming, Shen, Zhisen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439332/
https://www.ncbi.nlm.nih.gov/pubmed/32319147
http://dx.doi.org/10.1002/jcla.23322