Cargando…

Significant association between DHFR promoter methylation and ischemic stroke in a Chinese hypertensive population

OBJECTIVE: DHFR encodes dihydrofolate reductase, a major enzyme in the metabolism of folate, and is a candidate gene for ischemic stroke (IS). Therefore, we aimed to investigate the association between DHFR promoter methylation and IS in a Chinese population with primary hypertension. METHODS: Quant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Jingcen, Zhu, Hong, Xu, Guodong, Chen, Zhu, Li, Lian, Wang, Shuyu, Deng, Hongxia, Bao, Xiaoming, Shen, Zhisen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439332/ https://www.ncbi.nlm.nih.gov/pubmed/32319147 http://dx.doi.org/10.1002/jcla.23322

Ejemplares similares

Hypermethylation of dihydrofolate reductase promoter increases the risk of hypertension in Chinese
por: Xu, Guodong, et al.
Publicado: (2020)

Fast food consumption among young adolescents aged 12–15 years in 54 low- and middle-income countries
por: Li, Lian, et al.
Publicado: (2020)

Trends in the Prevalence of Hypertensive Heart Disease in China From 1990 to 2019: A Joinpoint and Age–Period–Cohort Analysis
por: Xu, Dan, et al.
Publicado: (2022)

The association, clinicopathological significance, and diagnostic value of CDH1 promoter methylation in head and neck squamous cell carcinoma: a meta-analysis of 23 studies
por: Shen, Zhisen, et al.
Publicado: (2016)

Identification of a new anoikis-related gene signature for prognostic significance in head and neck squamous carcinomas
por: Wei, Zhengyu, et al.
Publicado: (2023)

A comprehensive association analysis between homocysteine metabolic pathway gene methylation and ischemic stroke in a Chinese hypertensive population
por: Li, Bo, et al.
Publicado: (2020)

Long Non-Coding RNA Profiling in Laryngeal Squamous Cell Carcinoma and Its Clinical Significance: Potential Biomarkers for LSCC
por: Shen, Zhisen, et al.
Publicado: (2014)

Regulation of eDHFR-tagged proteins with trimethoprim PROTACs
por: Etersque, Jean M., et al.
Publicado: (2023)

A systematic review and meta-analysis approach on diagnostic value of MLH1 promoter methylation for head and neck squamous cell carcinoma
por: Li, Qun, et al.
Publicado: (2019)

The clinical significance of HOXA9 promoter hypermethylation in head and neck squamous cell carcinoma
por: Zhou, Chongchang, et al.
Publicado: (2019)

Association between systolic blood pressure and first ischemic stroke in the Chinese older hypertensive population
por: Yu, Yuling, et al.
Publicado: (2020)

Concurrence of Plasmodium falciparum dhfr and crt mutations in northern Ghana
por: Mockenhaupt, Frank P, et al.
Publicado: (2005)

Molecular docking studies on DMDP derivatives as human DHFR inhibitors
por: Srivastava, Vivek, et al.
Publicado: (2008)

DHFR Inhibitors: Reading the Past for Discovering Novel Anticancer Agents
por: Raimondi, Maria Valeria, et al.
Publicado: (2019)

Combined effect of hypertension and hyperuricemia on ischemic stroke in a rural Chinese population
por: Sun, Peng, et al.
Publicado: (2021)

Polymorphism of Drug Resistance Genes dhfr and dhps in Plasmodium falciparum Isolates among Chinese Migrant Workers Who Returned from Ghana in 2013
por: Quan, Hong, et al.
Publicado: (2023)

Methylation of the RIN3 Promoter is Associated with Transient Ischemic Stroke/Mild Ischemic Stroke with Early Cognitive Impairment
por: Miao, Meng, et al.
Publicado: (2021)

CDKN2B Methylation and Aortic Arch Calcification in Patients with Ischemic Stroke
por: Zhou, Shuyu, et al.
Publicado: (2017)

The association between homocysteine and ischemic stroke subtypes in Chinese: A meta-analysis
por: Zhang, Tao, et al.
Publicado: (2020)

Polymorphisms of Calgranulin Genes and Ischemic Stroke in a Chinese Population
por: Chen, Linfa, et al.
Publicado: (2022)

Chinese Ischemic Stroke Subclassification
por: Gao, S., et al.
Publicado: (2011)

Association study of polymorphisms in the ABO gene with ischemic stroke in the Chinese population
por: Ling, Xiaoming, et al.
Publicado: (2016)

Ligand Binding and Circular Permutation Modify Residue Interaction Network in DHFR
por: Hu, Zengjian, et al.
Publicado: (2007)

Expression and characterization of mouse prolactin (mPRL) in CHO dhfr- cells
por: Suzuki, Miriam Fussae, et al.
Publicado: (2014)

Structural and Dynamics Perspectives on the Binding of Substrate and Inhibitors in Mycobacterium tuberculosis DHFR
por: Sittikornpaiboon, Pimonluck, et al.
Publicado: (2017)

Theoretical Investigation of the Enantioselective Complexations between pfDHFR and Cycloguanil Derivatives
por: Kulatee, Suriyawut, et al.
Publicado: (2017)

Relationship Between Change in Serum Uric Acid and Ischemic Stroke in Chinese Hypertensive Patients
por: Tan, Qiu-hong, et al.
Publicado: (2021)

Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population
por: Zhao, Nan, et al.
Publicado: (2012)

A plant-based mutant huntingtin model-driven discovery of impaired expression of GTPCH and DHFR
por: Hung, Chiu-Yueh, et al.
Publicado: (2022)

CDKN2B methylation is associated with carotid artery calcification in ischemic stroke patients
por: Zhou, Shuyu, et al.
Publicado: (2016)

SHISA3 Promoter Methylation Is a Potential Diagnostic and Prognostic Biomarker for Laryngeal Squamous Cell Carcinoma
por: Shen, Zhisen, et al.
Publicado: (2017)

Disparate selection of mutations in the dihydrofolate reductase gene (dhfr) of Plasmodium ovale curtisi and P. o. wallikeri in Africa
por: Chen, Jing, et al.
Publicado: (2022)

High-Density Lipoprotein Cholesterol and the Risk of First Ischemic Stroke in a Chinese Hypertensive Population
por: Zhang, Yue, et al.
Publicado: (2021)

Plasmodium vivax dhfr Mutations among Isolates from Malarious Areas of Iran
por: Zaman, Jalal, et al.
Publicado: (2011)

Molecular surveillance of Plasmodium vivax dhfr and dhps mutations in isolates from Afghanistan
por: Zakeri, Sedigheh, et al.
Publicado: (2010)

Differences in selective pressure on dhps and dhfr drug resistant mutations in western Kenya
por: McCollum, Andrea M, et al.
Publicado: (2012)

Molecular docking analysis of phyto-constituents from Cannabis sativa with pfDHFR
por: David, Temitope.I, et al.
Publicado: (2018)

DHFR and MDR1 upregulation is associated with chemoresistance in osteosarcoma stem-like cells
por: Lee, Yu-Hsien, et al.
Publicado: (2017)

Non-antibiotic Small-Molecule Regulation of DHFR-Based Destabilizing Domains In Vivo
por: Peng, Hui, et al.
Publicado: (2019)

Roles Of EAAT1, DHFR, And Fetuin-A In The Pathogenesis, Progression And Prognosis Of Chondrosarcoma
por: He, Lile, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0cgat24cf0r9o3rap0djueuh14