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Design, Synthesis, and Biological Evaluation of Novel 7H-[1,2,4]Triazolo[3,4-b][1,3,4]thiadiazine Inhibitors as Antitumor Agents

[Image: see text] A series of novel anticancer hydrazinotriazolothiadiazine-based derivatives were designed based on the structure–activity relationship of the previously reported anticancer triazolothiadiazines. These derivatives were synthesized and biologically screened against full NCI-60 cancer...

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Detalles Bibliográficos
Autores principales: Ismail, Muhammad I., Mohamady, Samy, Samir, Nermin, Abouzid, Khaled A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439371/
https://www.ncbi.nlm.nih.gov/pubmed/32832771
http://dx.doi.org/10.1021/acsomega.0c01829