Co-delivery of IKBKE siRNA and cabazitaxel by hybrid nanocomplex inhibits invasiveness and growth of triple-negative breast cancer

IKBKE is an oncogene in triple-negative breast cancer (TNBC), and we demonstrate that IKBKE small interfering RNA (siRNA) inhibits the proliferation, migration, and invasion of TNBC cells. Despite the recent success of siRNA therapeutics targeting to the liver, there still remains a great challenge...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Zhen, Li, Yuanke, Liu, Hao, Jain, Akshay, Patel, Pratikkumar Vinodchandra, Cheng, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439402/
https://www.ncbi.nlm.nih.gov/pubmed/32832636
http://dx.doi.org/10.1126/sciadv.abb0616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439402/
https://www.ncbi.nlm.nih.gov/pubmed/32832636
http://dx.doi.org/10.1126/sciadv.abb0616

Ejemplares similares