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MRNIP is a replication fork protection factor

The remodeling of stalled replication forks to form four-way DNA junctions is an important component of the replication stress response. Nascent DNA at the regressed arms of these reversed forks is protected by RAD51 and the tumor suppressors BRCA1/2, and when this function is compromised, stalled f...

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Detalles Bibliográficos
Autores principales: Bennett, L. G., Wilkie, A. M., Antonopoulou, E., Ceppi, I., Sanchez, A., Vernon, E. G., Gamble, A., Myers, K. N., Collis, S. J., Cejka, P., Staples, C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439443/
https://www.ncbi.nlm.nih.gov/pubmed/32832601
http://dx.doi.org/10.1126/sciadv.aba5974