Cargando…

MRNIP is a replication fork protection factor

The remodeling of stalled replication forks to form four-way DNA junctions is an important component of the replication stress response. Nascent DNA at the regressed arms of these reversed forks is protected by RAD51 and the tumor suppressors BRCA1/2, and when this function is compromised, stalled f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bennett, L. G., Wilkie, A. M., Antonopoulou, E., Ceppi, I., Sanchez, A., Vernon, E. G., Gamble, A., Myers, K. N., Collis, S. J., Cejka, P., Staples, C. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439443/ https://www.ncbi.nlm.nih.gov/pubmed/32832601 http://dx.doi.org/10.1126/sciadv.aba5974

Ejemplares similares

MRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage Response
por: Staples, Christopher J., et al.
Publicado: (2016)

Homologous Recombination as a Replication Fork Escort: Fork-Protection and Recovery
por: Costes, Audrey, et al.
Publicado: (2012)

Replication Fork Reversal and Protection
por: Qiu, Shan, et al.
Publicado: (2021)

MRNIP condensates promote DNA double-strand break sensing and end resection
por: Wang, Yun-Long, et al.
Publicado: (2022)

Two replication fork remodeling pathways generate nuclease substrates for distinct fork protection factors
por: Liu, W., et al.
Publicado: (2020)

MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice
por: Kazi, Samina, et al.
Publicado: (2022)

A fork in the road: Where homologous recombination and stalled replication fork protection part ways
por: Tye, Stephanie, et al.
Publicado: (2021)

Stalled replication forks within heterochromatin require ATRX for protection
por: Huh, M S, et al.
Publicado: (2016)

Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork
por: Baretić, Domagoj, et al.
Publicado: (2020)

A protective role for BRCA2 at stalled replication forks
por: Chandramouly, Gurushankar, et al.
Publicado: (2011)

The fork protection complex recruits FACT to reorganize nucleosomes during replication
por: Safaric, Barbara, et al.
Publicado: (2022)

Chromosome replication: from ORC to fork
por: Nieduszynski, Conrad A, et al.
Publicado: (2001)

hCLK2 couples FANCD2 to stalled replication forks and functions in the mammalian S-phase checkpoint
por: Collis, SJ, et al.
Publicado: (2006)

DNA2 drives processing and restart of reversed replication forks in human cells
por: Thangavel, Saravanabhavan, et al.
Publicado: (2015)

Replication Fork Protection Factors Controlling R-Loop Bypass and Suppression
por: Chang, Emily Yun-Chia, et al.
Publicado: (2017)

Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed Genes
por: Alzu, Amaya, et al.
Publicado: (2012)

Local and global functions of Timeless and Tipin in replication fork protection
por: Leman, Adam R., et al.
Publicado: (2012)

Advances in understanding DNA processing and protection at stalled replication forks
por: Rickman, Kimberly, et al.
Publicado: (2019)

Avoiding chromosome pathology when replication forks collide
por: Rudolph, Christian J., et al.
Publicado: (2013)

Stability of blocked replication forks in vivo
por: Mettrick, Karla A., et al.
Publicado: (2016)

Replication fork instability and the consequences of fork collisions from rereplication
por: Alexander, Jessica L., et al.
Publicado: (2016)

Replication forks, chromatin loops and dormant replication origins
por: Blow, J Julian, et al.
Publicado: (2008)

SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks
por: Rageul, Julie, et al.
Publicado: (2020)

Replication dynamics of recombination-dependent replication forks
por: Naiman, Karel, et al.
Publicado: (2021)

BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression
por: Cohen, Stephanie M., et al.
Publicado: (2010)

Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability
por: Gaggioli, Vincent, et al.
Publicado: (2023)

UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity
por: Cipolla, Lina, et al.
Publicado: (2019)

Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery
por: Murphy, Anar K., et al.
Publicado: (2014)

Destabilization of the replication fork protection complex disrupts meiotic chromosome segregation
por: Escorcia, Wilber, et al.
Publicado: (2017)

CDK1 phosphorylates WRN at collapsed replication forks
por: Palermo, Valentina, et al.
Publicado: (2016)

SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection
por: Locke, Andrew J, et al.
Publicado: (2021)

Ku Stabilizes Replication Forks in the Absence of Brc1
por: Sánchez, Arancha, et al.
Publicado: (2015)

Repeat RNAs associate with replication forks and post-replicative DNA
por: Gylling, Helene M., et al.
Publicado: (2020)

Force regulated dynamics of RPA on a DNA fork
por: Kemmerich, Felix E., et al.
Publicado: (2016)

Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress
por: Peng, Min, et al.
Publicado: (2018)

The progression of replication forks at natural replication barriers in live bacteria
por: Moolman, M. Charl, et al.
Publicado: (2016)

Budding yeast Rif1 binds to replication origins and protects DNA at blocked replication forks
por: Hiraga, Shin‐ichiro, et al.
Publicado: (2018)

Abro1 maintains genome stability and limits replication stress by protecting replication fork stability
por: Xu, Shengfeng, et al.
Publicado: (2017)

Delineation of the Ancestral Tus-Dependent Replication Fork Trap
por: Toft, Casey J., et al.
Publicado: (2021)

Replication Fork Reversal after Replication–Transcription Collision
por: De Septenville, Anne L., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_hcohprn0o3v14abc9efu0hssbk