Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

Pulmonary fibrosis (PF) is a form of chronic lung disease characterized by pathologic epithelial remodeling and accumulation of extracellular matrix (ECM). To comprehensively define the cell types, mechanisms, and mediators driving fibrotic remodeling in lungs with PF, we performed single-cell RNA s...

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Detalles Bibliográficos
Autores principales: Habermann, Arun C., Gutierrez, Austin J., Bui, Linh T., Yahn, Stephanie L., Winters, Nichelle I., Calvi, Carla L., Peter, Lance, Chung, Mei-I, Taylor, Chase J., Jetter, Christopher, Raju, Latha, Roberson, Jamie, Ding, Guixiao, Wood, Lori, Sucre, Jennifer M. S., Richmond, Bradley W., Serezani, Ana P., McDonnell, Wyatt J., Mallal, Simon B., Bacchetta, Matthew J., Loyd, James E., Shaver, Ciara M., Ware, Lorraine B., Bremner, Ross, Walia, Rajat, Blackwell, Timothy S., Banovich, Nicholas E., Kropski, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439444/
https://www.ncbi.nlm.nih.gov/pubmed/32832598
http://dx.doi.org/10.1126/sciadv.aba1972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439444/
https://www.ncbi.nlm.nih.gov/pubmed/32832598
http://dx.doi.org/10.1126/sciadv.aba1972

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