Pathogenesis of Human Papillomaviruses Requires the ATR/p62 Autophagy-Related Pathway

High-risk human papillomaviruses (HPVs) constitutively activate the ataxia telangiectasia and Rad3-related (ATR) DNA damage response pathway, and this is required for viral replication. In fibroblasts, activated ATR regulates transcription of inflammatory genes through its negative effects on the au...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Shiyuan, Li, Yan, Kaminski, Paul J., Andrade, Jorge, Laimins, Laimonis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439466/
https://www.ncbi.nlm.nih.gov/pubmed/32788179
http://dx.doi.org/10.1128/mBio.01628-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439466/
https://www.ncbi.nlm.nih.gov/pubmed/32788179
http://dx.doi.org/10.1128/mBio.01628-20

Ejemplares similares