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Pathogenesis of Human Papillomaviruses Requires the ATR/p62 Autophagy-Related Pathway
High-risk human papillomaviruses (HPVs) constitutively activate the ataxia telangiectasia and Rad3-related (ATR) DNA damage response pathway, and this is required for viral replication. In fibroblasts, activated ATR regulates transcription of inflammatory genes through its negative effects on the au...
Autores principales: | Hong, Shiyuan, Li, Yan, Kaminski, Paul J., Andrade, Jorge, Laimins, Laimonis A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439466/ https://www.ncbi.nlm.nih.gov/pubmed/32788179 http://dx.doi.org/10.1128/mBio.01628-20 |
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