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Differential Alphavirus Defective RNA Diversity between Intracellular and Extracellular Compartments Is Driven by Subgenomic Recombination Events

Alphaviruses are positive-sense RNA arboviruses that can cause either a chronic arthritis or a potentially lethal encephalitis. Like other RNA viruses, alphaviruses produce truncated, defective viral RNAs featuring large deletions during replication. These defective RNAs (D-RNAs) have primarily been...

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Detalles Bibliográficos
Autores principales: Langsjoen, R. M., Muruato, A. E., Kunkel, S. R., Jaworski, E., Routh, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439471/
https://www.ncbi.nlm.nih.gov/pubmed/32817101
http://dx.doi.org/10.1128/mBio.00731-20