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Cryo-EM structure of the calcium homeostasis modulator 1 channel
Calcium homeostasis modulator 1 (CALHM1) is a voltage-gated ATP release channel that plays an important role in neural gustatory signaling and the pathogenesis of Alzheimer’s disease. Here, we present a cryo–electron microscopy structure of full-length Ca(2+)-free CALHM1 from Danio rerio at an overa...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439498/ https://www.ncbi.nlm.nih.gov/pubmed/32832630 http://dx.doi.org/10.1126/sciadv.aba8161 |