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Cryo-EM structure of the calcium homeostasis modulator 1 channel

Calcium homeostasis modulator 1 (CALHM1) is a voltage-gated ATP release channel that plays an important role in neural gustatory signaling and the pathogenesis of Alzheimer’s disease. Here, we present a cryo–electron microscopy structure of full-length Ca(2+)-free CALHM1 from Danio rerio at an overa...

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Detalles Bibliográficos
Autores principales:	Ren, Yue, Wen, Tianlei, Xi, Zhiqin, Li, Shunjin, Lu, Jing, Zhang, Xing, Yang, Xue, Shen, Yuequan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439498/ https://www.ncbi.nlm.nih.gov/pubmed/32832630 http://dx.doi.org/10.1126/sciadv.aba8161

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