Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

We provide a single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung disease, by profiling 312,928 cells from 32 IPF, 28 smoker and nonsmoker controls, and 18 chronic obstructive pulmonary disease (COPD) lungs. Among epithelial cells enriched in IPF, we identify a previou...

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Detalles Bibliográficos
Autores principales: Adams, Taylor S., Schupp, Jonas C., Poli, Sergio, Ayaub, Ehab A., Neumark, Nir, Ahangari, Farida, Chu, Sarah G., Raby, Benjamin A., DeIuliis, Giuseppe, Januszyk, Michael, Duan, Qiaonan, Arnett, Heather A., Siddiqui, Asim, Washko, George R., Homer, Robert, Yan, Xiting, Rosas, Ivan O., Kaminski, Naftali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439502/
https://www.ncbi.nlm.nih.gov/pubmed/32832599
http://dx.doi.org/10.1126/sciadv.aba1983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439502/
https://www.ncbi.nlm.nih.gov/pubmed/32832599
http://dx.doi.org/10.1126/sciadv.aba1983

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