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Nitric oxide debilitates the neuropathogenic schistosome Trichobilharzia regenti in mice, partly by inhibiting its vital peptidases

BACKGROUND: Avian schistosomes, the causative agents of human cercarial dermatitis (or swimmer’s itch), die in mammals but the mechanisms responsible for parasite elimination are unknown. Here we examined the role of reactive nitrogen species, nitric oxide (NO) and peroxynitrite, in the immune respo...

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Detalles Bibliográficos
Autores principales: Macháček, Tomáš, Šmídová, Barbora, Pankrác, Jan, Majer, Martin, Bulantová, Jana, Horák, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439556/
https://www.ncbi.nlm.nih.gov/pubmed/32819437
http://dx.doi.org/10.1186/s13071-020-04279-9