Accelerating thrombolysis using a precision and clot-penetrating drug delivery strategy by nanoparticle-shelled microbubbles

Conventional thrombolytic drugs for vascular blockage such as tissue plasminogen activator (tPA) are challenged by the low bioavailability, off-target side effects and limited penetration in thrombi, leading to delayed recanalization. We hypothesize that these challenges can be addressed with the ta...

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Detalles Bibliográficos
Autores principales: Wang, Siyu, Guo, Xixi, Xiu, Weijun, Liu, Yang, Ren, Lili, Xiao, Huaxin, Yang, Fang, Gao, Yu, Xu, Chenjie, Wang, Lianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439573/
https://www.ncbi.nlm.nih.gov/pubmed/32832678
http://dx.doi.org/10.1126/sciadv.aaz8204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439573/
https://www.ncbi.nlm.nih.gov/pubmed/32832678
http://dx.doi.org/10.1126/sciadv.aaz8204

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