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A reanalysis of nanoparticle tumor delivery using classical pharmacokinetic metrics

Nanoparticle (NP) delivery to solid tumors has recently been questioned. To better understand the magnitude of NP tumor delivery, we reanalyzed published murine NP tumor pharmacokinetic (PK) data used in the Wilhelm et al. study. Studies included in their analysis reporting matched tumor and blood c...

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Detalles Bibliográficos
Autores principales: Price, Lauren S. L., Stern, Stephan T., Deal, Allison M., Kabanov, Alexander V., Zamboni, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439617/
https://www.ncbi.nlm.nih.gov/pubmed/32832614
http://dx.doi.org/10.1126/sciadv.aay9249