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Hypoxia inducible factor-1 (HIF-1α) reduced inflammation in spinal cord injury via miR-380-3p/ NLRP3 by Circ 0001723

BACKGROUND: Spinal cord injury (SCI) is a severe central nervous system trauma. The present study aimed to evaluate the effect of HIF-1α on inflammation in spinal cord injury (SCI) to uncover the molecular mechanisms of anti-inflammation. RESULTS: HIF-1α was reduced in SCI model rats and HIF-1α acti...

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Detalles Bibliográficos
Autores principales: Li, Xigong, Lou, Xianfeng, Xu, Sanzhong, Du, Junhua, Wu, Junsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439692/
https://www.ncbi.nlm.nih.gov/pubmed/32819442
http://dx.doi.org/10.1186/s40659-020-00302-6