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Cis and trans effects differentially contribute to the evolution of promoters and enhancers

BACKGROUND: Gene expression differences between species are driven by both cis and trans effects. Whereas cis effects are caused by genetic variants located on the same DNA molecule as the target gene, trans effects are due to genetic variants that affect diffusible elements. Previous studies have m...

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Detalles Bibliográficos
Autores principales: Mattioli, Kaia, Oliveros, Winona, Gerhardinger, Chiara, Andergassen, Daniel, Maass, Philipp G., Rinn, John L., Melé, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439725/
https://www.ncbi.nlm.nih.gov/pubmed/32819422
http://dx.doi.org/10.1186/s13059-020-02110-3