Cargando…
Cis and trans effects differentially contribute to the evolution of promoters and enhancers
BACKGROUND: Gene expression differences between species are driven by both cis and trans effects. Whereas cis effects are caused by genetic variants located on the same DNA molecule as the target gene, trans effects are due to genetic variants that affect diffusible elements. Previous studies have m...
Autores principales: | Mattioli, Kaia, Oliveros, Winona, Gerhardinger, Chiara, Andergassen, Daniel, Maass, Philipp G., Rinn, John L., Melé, Marta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439725/ https://www.ncbi.nlm.nih.gov/pubmed/32819422 http://dx.doi.org/10.1186/s13059-020-02110-3 |
Ejemplares similares
-
High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity
por: Mattioli, Kaia, et al.
Publicado: (2019) -
Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs
por: Melé, Marta, et al.
Publicado: (2017) -
Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency
por: Haswell, Jeffrey R., et al.
Publicado: (2021) -
High-throughput functional analysis of regulatory variants using a massively parallel reporter assay
por: Delfosse, Kate, et al.
Publicado: (2023) -
In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation
por: Andergassen, Daniel, et al.
Publicado: (2019)