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MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin

Accumulating evidence has pointed out that metastasis is the leading cause of death in several malignant tumor, including CRC. During CRC, metastatic capacity is closely correlated with reprogrammed energy metabolism. Mitochondrial Pyruvate Carrier 1 (MPC1), as the carrier of transporting pyruvate i...

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Detalles Bibliográficos
Autores principales: Tian, Guang-Ang, Xu, Chun-Jie, Zhou, Kai-Xia, Zhang, Zhi-Gang, Gu, Jian-Ren, Zhang, Xue-Li, Wang, Ya-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439788/
https://www.ncbi.nlm.nih.gov/pubmed/32851100
http://dx.doi.org/10.1155/2020/8340329