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MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin
Accumulating evidence has pointed out that metastasis is the leading cause of death in several malignant tumor, including CRC. During CRC, metastatic capacity is closely correlated with reprogrammed energy metabolism. Mitochondrial Pyruvate Carrier 1 (MPC1), as the carrier of transporting pyruvate i...
Autores principales: | Tian, Guang-Ang, Xu, Chun-Jie, Zhou, Kai-Xia, Zhang, Zhi-Gang, Gu, Jian-Ren, Zhang, Xue-Li, Wang, Ya-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439788/ https://www.ncbi.nlm.nih.gov/pubmed/32851100 http://dx.doi.org/10.1155/2020/8340329 |
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