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Integrative analyses of SARS-CoV-2 genomes from different geographical locations reveal unique features potentially consequential to host-virus interaction, pathogenesis and clues for novel therapies

We have performed an integrative analysis of SARS-CoV-2 genome sequences from different countries. Apart from mutational analysis, we have predicted host antiviral miRNAs targeting virus genes, PTMs in the virus proteins and antiviral peptides. A comparison of the analyses with other coronavirus gen...

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Detalles Bibliográficos
Autores principales: Sardar, Rahila, Satish, Deepshikha, Birla, Shweta, Gupta, Dinesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439967/
https://www.ncbi.nlm.nih.gov/pubmed/32844125
http://dx.doi.org/10.1016/j.heliyon.2020.e04658