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ACE2 coding variants in different populations and their potential impact on SARS-CoV-2 binding affinity

The susceptibility of different populations to SARS-CoV-2 infection is not yet understood. Here, we combined ACE2 coding variants' analysis in different populations and computational chemistry calculations to probe the effects on SARS-CoV-2/ACE2 interaction. ACE2-K26R; which is most frequent in...

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Detalles Bibliográficos
Autores principales: Ali, Fedaa, Elserafy, Menattallah, Alkordi, Mohamed H., Amin, Muhamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439997/
https://www.ncbi.nlm.nih.gov/pubmed/32844124
http://dx.doi.org/10.1016/j.bbrep.2020.100798