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Replicase 1a gene plays a critical role in pathogenesis of avian coronavirus infectious bronchitis virus
Avian coronavirus infectious bronchitis virus (IBV) is an important pathogen threatening poultry production worldwide. Here, two recombinant IBVs (rYN-1a-aYN and rYN-1b-aYN) were generated in which ORF1a or ORF1b of the virulent YN genome were replaced by the corresponding regions from the attenuate...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440038/ https://www.ncbi.nlm.nih.gov/pubmed/32853833 http://dx.doi.org/10.1016/j.virol.2020.08.009 |