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Replicase 1a gene plays a critical role in pathogenesis of avian coronavirus infectious bronchitis virus

Avian coronavirus infectious bronchitis virus (IBV) is an important pathogen threatening poultry production worldwide. Here, two recombinant IBVs (rYN-1a-aYN and rYN-1b-aYN) were generated in which ORF1a or ORF1b of the virulent YN genome were replaced by the corresponding regions from the attenuate...

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Detalles Bibliográficos
Autores principales:	Zhao, Jing, Zhang, Keran, Cheng, Jinlong, Jia, Wenfeng, Zhao, Ye, Zhang, Guozhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440038/ https://www.ncbi.nlm.nih.gov/pubmed/32853833 http://dx.doi.org/10.1016/j.virol.2020.08.009

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