Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite

Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role. We adapted a CRISPR‐based proteomics approach to identify novel factors associated with var genes in their natural chro...

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Detalles Bibliográficos
Autores principales: Bryant, Jessica M, Baumgarten, Sebastian, Dingli, Florent, Loew, Damarys, Sinha, Ameya, Claës, Aurélie, Preiser, Peter R, Dedon, Peter C, Scherf, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440042/
https://www.ncbi.nlm.nih.gov/pubmed/32816370
http://dx.doi.org/10.15252/msb.20209569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440042/
https://www.ncbi.nlm.nih.gov/pubmed/32816370
http://dx.doi.org/10.15252/msb.20209569

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