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Preclinical mouse models for immunotherapeutic and non-immunotherapeutic drug development for pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is in urgent need of better diagnostic and therapeutic methods due to its late diagnosis, limited treatment options and poor prognosis. Finding the right animal models to recapitulate the tumor molecular pathogenesis and tumor microenvironment (TME) complexity...

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Detalles Bibliográficos
Autores principales: He, Mengni, Henderson, MacKenzie, Muth, Stephen, Murphy, Adrian, Zheng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440242/
https://www.ncbi.nlm.nih.gov/pubmed/32832900
http://dx.doi.org/10.21037/apc.2020.03.03