Gain-of-function mutation in SCN11A causes itch and affects neurogenic inflammation and muscle function in Scn11a(+/L799P) mice

Mutations in the genes encoding for voltage-gated sodium channels cause profound sensory disturbances and other symptoms dependent on the distribution of a particular channel subtype in different organs. Humans with the gain-of-function mutation p.Leu811Pro in SCN11A (encoding for the voltage-gated...

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Detalles Bibliográficos
Autores principales: Ebbinghaus, Matthias, Tuchscherr, Lorena, Segond von Banchet, Gisela, Liebmann, Lutz, Adams, Volker, Gajda, Mieczyslaw, Hübner, Christian A., Kurth, Ingo, Schaible, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440628/
https://www.ncbi.nlm.nih.gov/pubmed/32817686
http://dx.doi.org/10.1371/journal.pone.0237101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440628/
https://www.ncbi.nlm.nih.gov/pubmed/32817686
http://dx.doi.org/10.1371/journal.pone.0237101

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