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The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions
Leprosy is a chronic disease caused by Mycobacterium leprae. Worldwide, more than 200,000 new patients are affected by leprosy annually, making it the second most common mycobacterial disease after tuberculosis. The MHC/HLA region has been consistently identified as carrying major leprosy susceptibi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440659/ https://www.ncbi.nlm.nih.gov/pubmed/32776973 http://dx.doi.org/10.1371/journal.ppat.1008818 |