Cargando…
The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions
Leprosy is a chronic disease caused by Mycobacterium leprae. Worldwide, more than 200,000 new patients are affected by leprosy annually, making it the second most common mycobacterial disease after tuberculosis. The MHC/HLA region has been consistently identified as carrying major leprosy susceptibi...
Autores principales: | Dallmann-Sauer, Monica, Fava, Vinicius M., Gzara, Chaïma, Orlova, Marianna, Van Thuc, Nguyen, Thai, Vu Hong, Alcaïs, Alexandre, Abel, Laurent, Cobat, Aurélie, Schurr, Erwin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440659/ https://www.ncbi.nlm.nih.gov/pubmed/32776973 http://dx.doi.org/10.1371/journal.ppat.1008818 |
Ejemplares similares
-
Family-based genome-wide association study of leprosy in Vietnam
por: Gzara, Chaima, et al.
Publicado: (2020) -
Deep resequencing identifies candidate functional genes in leprosy GWAS loci
por: Fava, Vinicius M., et al.
Publicado: (2021) -
A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy
por: Fava, Vinicius M., et al.
Publicado: (2016) -
Pauci- and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases
por: Gaschignard, Jean, et al.
Publicado: (2016) -
Gene Set Signature of Reversal Reaction Type I in Leprosy Patients
por: Orlova, Marianna, et al.
Publicado: (2013)