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Cryo-EM structure of the human concentrative nucleoside transporter CNT3

Concentrative nucleoside transporters (CNTs), members of the solute carrier (SLC) 28 transporter family, facilitate the salvage of nucleosides and therapeutic nucleoside derivatives across the plasma membrane. Despite decades of investigation, the structures of human CNTs remain unknown. We determin...

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Detalles Bibliográficos
Autores principales: Zhou, Yanxia, Liao, Lianghuan, Wang, Chen, Li, Jialu, Chi, Pengliang, Xiao, Qingjie, Liu, Qingting, Guo, Li, Sun, Linfeng, Deng, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440666/
https://www.ncbi.nlm.nih.gov/pubmed/32776918
http://dx.doi.org/10.1371/journal.pbio.3000790