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In silico co-factor balance estimation using constraint-based modelling informs metabolic engineering in Escherichia coli
In the growing field of metabolic engineering, where cells are treated as ‘factories’ that synthesize industrial compounds, it is essential to consider the ability of the cells’ native metabolism to accommodate the demands of synthetic pathways, as these pathways will alter the homeostasis of cellul...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440669/ https://www.ncbi.nlm.nih.gov/pubmed/32776925 http://dx.doi.org/10.1371/journal.pcbi.1008125 |