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Gemcitabine/nab-paclitaxel with pamrevlumab: a novel drug combination and trial design for the treatment of locally advanced pancreatic cancer

PURPOSE: Pancreatic ductal adenocarcinomas exhibit a high degree of desmoplasia due to extensive extracellular matrix deposition. Encasement of mesenteric vessels by stroma in locally advanced pancreatic cancer (LAPC) prevents surgical resection. This study sought to determine if the addition of a m...

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Detalles Bibliográficos
Autores principales: Picozzi, Vincent, Alseidi, Adnan, Winter, Jordan, Pishvaian, Michael, Mody, Kabir, Glaspy, John, Larson, Timothy, Matrana, Marc, Carney, Mairead, Porter, Seth, Kouchakji, Elias, Rocha, Flavio, Carrier, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440698/
https://www.ncbi.nlm.nih.gov/pubmed/32817130
http://dx.doi.org/10.1136/esmoopen-2019-000668