Generation of Viable Candida albicans Mutants Lacking the “Essential” Protein Kinase Snf1 by Inducible Gene Deletion

The protein kinase Snf1, a member of the highly conserved AMP-activated protein kinase family, is a central regulator of metabolic adaptation. In the pathogenic yeast Candida albicans, Snf1 is considered to be essential, as previous attempts by different research groups to generate homozygous snf1Δ...

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Detalles Bibliográficos
Autores principales: Mottola, Austin, Schwanfelder, Sonja, Morschhäuser, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440847/
https://www.ncbi.nlm.nih.gov/pubmed/32817381
http://dx.doi.org/10.1128/mSphere.00805-20