Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo

T regulatory (Treg) cells play vital roles in modulating immunity and tissue homeostasis. Their actions depend on TCR recognition of peptide-MHC molecules; yet the degree of peptide specificity of Treg-cell function, and whether Treg ligands can be used to manipulate Treg cell biology are unknown. H...

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Detalles Bibliográficos
Autores principales: Fernandes, Ricardo A, Li, Chaoran, Wang, Gang, Yang, Xinbo, Savvides, Christina S, Glassman, Caleb R, Dong, Shen, Luxenberg, Eric, Sibener, Leah V, Birnbaum, Michael E, Benoist, Christophe, Mathis, Diane, Garcia, K Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440915/
https://www.ncbi.nlm.nih.gov/pubmed/32773038
http://dx.doi.org/10.7554/eLife.58463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440915/
https://www.ncbi.nlm.nih.gov/pubmed/32773038
http://dx.doi.org/10.7554/eLife.58463

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