MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity

Localized prostate cancer develops very slowly in most men, with the androgen receptor (AR) and MYC transcription factors amongst the most well-characterized drivers of prostate tumorigenesis. Canonically, MYC up-regulation in luminal prostate cancer cells functions to oppose the terminally differen...

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Detalles Bibliográficos
Autores principales: Whitlock, Nichelle C., Trostel, Shana Y., Wilkinson, Scott, Terrigino, Nicholas T., Hennigan, S. Thomas, Lake, Ross, Carrabba, Nicole V., Atway, Rayann, Walton, Elizabeth D., Gryder, Berkley E., Capaldo, Brian J., Ye, Huihui, Sowalsky, Adam G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441006/
https://www.ncbi.nlm.nih.gov/pubmed/32681068
http://dx.doi.org/10.1038/s41388-020-01389-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441006/
https://www.ncbi.nlm.nih.gov/pubmed/32681068
http://dx.doi.org/10.1038/s41388-020-01389-7

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