Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer

Cervical cancer (CC) remains highest in the mortality of female reproductive system cancers, while cisplatin (CDDP) resistance is the one of main reasons for the lethality. Preceding evidence has supported that karyopherins are associated with chemoresistance. In this study, we simultaneously compar...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Liu, Fei, Xu, Qinyang, Yang, Bikang, Li, Xiao, Jiang, Shuheng, Hu, Lipeng, Zhang, Xueli, Zhu, Lili, Li, Qing, Zhu, Xiaolu, Shao, Hongfang, Dai, Miao, Shen, Yifei, Ni, Bo, Wang, Shuai, Zhang, Zhigang, Teng, Yincheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441007/
https://www.ncbi.nlm.nih.gov/pubmed/32661323
http://dx.doi.org/10.1038/s41388-020-1384-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441007/
https://www.ncbi.nlm.nih.gov/pubmed/32661323
http://dx.doi.org/10.1038/s41388-020-1384-3

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