Cargando…

β-catenin S45F mutation results in apoptotic resistance

Wnt/β-catenin signaling is one of the key cascades regulating embryogenesis and tissue homeostasis; it has also been intimately associated with carcinogenesis. This pathway is deregulated in several tumors, including colorectal cancer, breast cancer, and desmoid tumors. It has been shown that CTNNB1...

Descripción completa

Detalles Bibliográficos
Autores principales: Braggio, Danielle, Zewdu, Abeba, Londhe, Priya, Yu, Peter, Lopez, Gonzalo, Batte, Kara, Koller, David, Costas Casal de Faria, Fernanda, Casadei, Lucia, Strohecker, Anne M., Lev, Dina, Pollock, Raphael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441052/
https://www.ncbi.nlm.nih.gov/pubmed/32651460
http://dx.doi.org/10.1038/s41388-020-1382-5