Cargando…

β-catenin S45F mutation results in apoptotic resistance

Wnt/β-catenin signaling is one of the key cascades regulating embryogenesis and tissue homeostasis; it has also been intimately associated with carcinogenesis. This pathway is deregulated in several tumors, including colorectal cancer, breast cancer, and desmoid tumors. It has been shown that CTNNB1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Braggio, Danielle, Zewdu, Abeba, Londhe, Priya, Yu, Peter, Lopez, Gonzalo, Batte, Kara, Koller, David, Costas Casal de Faria, Fernanda, Casadei, Lucia, Strohecker, Anne M., Lev, Dina, Pollock, Raphael E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441052/ https://www.ncbi.nlm.nih.gov/pubmed/32651460 http://dx.doi.org/10.1038/s41388-020-1382-5

Ejemplares similares

Preclinical efficacy of the Wnt/β-catenin pathway inhibitor BC2059 for the treatment of desmoid tumors
por: Braggio, Danielle Almeida, et al.
Publicado: (2022)

Mocetinostat combined with gemcitabine for the treatment of leiomyosarcoma: Preclinical correlates
por: Lopez, Gonzalo, et al.
Publicado: (2017)

HDAC8, A Potential Therapeutic Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors (MPNST)
por: Lopez, Gonzalo, et al.
Publicado: (2015)

Verticillin A Inhibits Leiomyosarcoma and Malignant Peripheral Nerve Sheath Tumor Growth via Induction of Apoptosis
por: Zewdu, A, et al.
Publicado: (2016)

miR-133a function in the pathogenesis of dedifferentiated liposarcoma
por: Yu, Peter Y., et al.
Publicado: (2018)

Targetable Pathways in the Treatment of Retroperitoneal Liposarcoma
por: Casadei, Lucia, et al.
Publicado: (2022)

Cross‐flow microfiltration for isolation, selective capture and release of liposarcoma extracellular vesicles
por: Casadei, Lucia, et al.
Publicado: (2021)

A call for curricular reform: Recognising the importance of race‐based medical education
por: Inshaar, Hafza, et al.
Publicado: (2022)

Targeting the notch pathway: A potential therapeutic approach for desmoid tumors
por: Shang, Hui, et al.
Publicado: (2015)

MiR-145, a new regulator of the DNA Fragmentation Factor-45 (DFF45)-mediated apoptotic network
por: Zhang, Jianjun, et al.
Publicado: (2010)

Balloon atrial septostomy through internal jugular vein in a 45-day-old child with transposition of great arteries
por: Padhi, Sumanta S, et al.
Publicado: (2010)

In situ hybridization to detect DNA amplification in extracellular vesicles
por: Casadei, Lucia, et al.
Publicado: (2022)

Cracking the riddle of dedifferentiated liposarcoma: is EV-MDM2 a key?
por: Casadei, Lucia, et al.
Publicado: (2020)

β-Catenin Phosphorylated at Serine 45 Is Spatially Uncoupled from β-Catenin Phosphorylated in the GSK3 Domain: Implications for Signaling
por: Maher, Meghan T., et al.
Publicado: (2010)

Cleavage of Armadillo/beta-catenin by the caspase DrICE in Drosophila apoptotic epithelial cells
por: Kessler, Thomas, et al.
Publicado: (2009)

Sequential association of myogenic regulatory factors and E proteins at muscle-specific genes
por: Londhe, Priya, et al.
Publicado: (2011)

Novel Systemic Therapies in Advanced Liposarcoma: A Review of Recent Clinical Trial Results
por: Tseng, William W., et al.
Publicado: (2013)

Letter from Buena Vista, Stephenson County, Illinois
por: Strohecker, Chas. G.
Publicado: (1854)

Management of Cancer Cachexia: Attempting to Develop New Pharmacological Agents for New Effective Therapeutic Options
por: Marceca, Gioacchino P., et al.
Publicado: (2020)

CT45A1 promotes the metastasis of osteosarcoma cells in vitro and in vivo through β-catenin
por: Wen, Mingxin, et al.
Publicado: (2021)

The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients
por: Krüger, Maximilian, et al.
Publicado: (2016)

Nuclear Receptor CAR Represses TNFα-Induced Cell Death by Interacting with the Anti-Apoptotic GADD45B
por: Yamamoto, Yukio, et al.
Publicado: (2010)

DNA microarray expression profiling of a new t(8;13) AML case allows identification of possible leukemogenic transformation markers
por: Pozzo, Aline Rangel, et al.
Publicado: (2017)

Oncogenic Serine 45-Deleted β-Catenin Remains Susceptible to Wnt Stimulation and APC Regulation in Human Colonocytes
por: Parker, Taybor W., et al.
Publicado: (2020)

Persistent Inhibition of ABL Tyrosine Kinase Causes Enhanced Apoptotic Response to TRAIL and Disrupts the Pro-Apoptotic Effect of Chloroquine
por: Sridevi, Priya, et al.
Publicado: (2013)

β-catenin promotes endothelial survival by regulating eNOS activity and flow-dependent anti-apoptotic gene expression
por: Tajadura, Virginia, et al.
Publicado: (2020)

Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice
por: Qiao, Yu, et al.
Publicado: (2018)

Cancer-Derived Extracellular Vesicles: Their Role in Sarcoma
por: Adib, Anita, et al.
Publicado: (2022)

Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin
por: Yang, Xiaotong, et al.
Publicado: (2020)

PtdIns(4,5)P(2) and PtdIns3P coordinate to regulate phagosomal sealing for apoptotic cell clearance
por: Cheng, Shiya, et al.
Publicado: (2015)

Myricetin Exerts its Apoptotic Effects on MCF-7 Breast Cancer Cells through Evoking the BRCA1-GADD45 Pathway
por: Sajedi, Nayereh, et al.
Publicado: (2020)

The Interface between BCR-ABL-Dependent and -Independent Resistance Signaling Pathways in Chronic Myeloid Leukemia
por: Nestal de Moraes, Gabriela, et al.
Publicado: (2012)

Regulation of Wnt/β‐catenin signalling by tankyrase‐dependent poly(ADP‐ribosyl)ation and scaffolding
por: Mariotti, Laura, et al.
Publicado: (2017)

The hepatocyte growth factor receptor as a potential therapeutic target for dedifferentiated liposarcoma
por: Bill, Kate Lynn J., et al.
Publicado: (2015)

Applications of superconducting technologies to particle detection
por: Braggio, Caterina
Publicado: (2022)

Biotin-Decorated PAMAM G4.5 Dendrimer Nanoparticles to Enhance the Delivery, Anti-Proliferative, and Apoptotic Effects of Chemotherapeutic Drug in Cancer Cells
por: Hanurry, Endiries Yibru, et al.
Publicado: (2020)

Anti-Apoptotic Effects of Osteopontin via the Up-Regulation of AKT/mTOR/β-Catenin Loop in Acute Myeloid Leukemia Cells
por: Zahed Panah, Mahdi, et al.
Publicado: (2017)

Nucleoporin 62-Like Protein Is Required for the Development of Pharyngeal Arches through Regulation of Wnt/β-Catenin Signaling and Apoptotic Homeostasis in Zebrafish
por: Yang, Xiaojie, et al.
Publicado: (2019)

Are membranes non-apoptotic compartments for apoptotic caspases?
por: Bergmann, Andreas
Publicado: (2018)

Parkin Promotes Degradation of the Mitochondrial Pro-Apoptotic ARTS Protein
por: Kemeny, Stav, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_e8j27m6bkhj6s9b6k5ddcce69g