Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing

Sensing and responding to temperature is crucial in biology. The TRPV1 ion channel is a well-studied heat-sensing receptor that is also activated by vanilloid compounds, including capsaicin. Despite significant interest, the molecular underpinnings of thermosensing have remained elusive. The TRPV1 S...

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Detalles Bibliográficos
Autores principales: Kim, Minjoo, Sisco, Nicholas J., Hilton, Jacob K., Montano, Camila M., Castro, Manuel A., Cherry, Brian R., Levitus, Marcia, Van Horn, Wade D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441067/
https://www.ncbi.nlm.nih.gov/pubmed/32820172
http://dx.doi.org/10.1038/s41467-020-18026-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7441067/
https://www.ncbi.nlm.nih.gov/pubmed/32820172
http://dx.doi.org/10.1038/s41467-020-18026-2

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